From Monkey Island wiki
There are no permanent settlements on Spoon Isle, but a few Vaycaylian artifacts remain in the jungle, including a fishing well holding the Cranky Fish Summoning Artifact, a barbecue and an altar holding the Wise Turtle Summoning Artifact. There is a cannon on the beach, which LeChuck uses as part of Elaine Marley's plan to weaken the siege on the islands.
When Guybrush Threepwood first arrives on Spoon he finds Trenchfoot and Hardtack, two of Captain McGillicutty's poxed pirates, debating over who gets to decide where to bury the Sea Horse Summoning Artifact that has been entrusted to them. Three other of McGillicutty's pirates are around and later attack LeChuck when they believe he has another of the artifacts.
In "Rise of the Pirate God", it is believed that LeChuck has returned after the cure of the Pox and killed the entire Spoon Isle Trio before leaving the island to destroy Spinner Cay.